What is BitLocker? BitLocker (and BitLocker To Go) is a whole-disk encryption program that encrypts data on a Windows PC or USB flash drive to prevent unauthorized access from anyone that does not have the decryption key or user’s account credentials.SEE: Encryption policy (Tech Pro Research) Executive summary Check this resource periodically, because we’ll update it when Microsoft releases new information throughout BitLocker’s development lifecycle. This comprehensive guide covers essential information about BitLocker, including features and system requirements. BitLocker To Go, a subset of BitLocker, works in much the same fashion except it is used to protect data on external media, such as USB flash drives and requires a key in order to decrypt data before it can be successfully read. Microsoft’s BitLocker allows for full-disk encryption, which means data stored on the drive will be protected using the newest, strongest encryption standards to prevent unauthorized access.